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D-serine deaminase is a stringent selective marker in genetic crosses
1Department of Microbiology, New York University School of Medicine, New York 10016.
Journal of Bacteriology
|January 1, 1995
Abstract:
The presence of the locus for D-serine deaminase (dsd) renders bacteria resistant to growth inhibition by D-serine and enables them to grow with D-serine as the sole nitrogen source. The two properties permit stringent selection in genetic crosses and make the D-serine deaminase gene an excellent marker, especially in the construction of strains for which the use of antibiotic resistance genes as selective markers is not allowed.