[Evaluation of midazolam premedication for preoperative anxiolysis]

To evaluate the anxiolysis property of midazolam, 60 patients undergoing minor gynecological surgery were given midazolam 0 mg (n = 20), 2.5 mg (n = 20) or 4 mg (n = 20) intramuscularly as premedication 1 h before their entrance to operating theater. The degree of anxiety was evaluated objectively using the State-Trait Anxiety Inventory (STAI). STAI test was performed twice: on the day before operation and 1 h after receiving preanesthetic premedication. In only midazolam 4 mg group, anxiety was reduced significantly in the operating room compared to the day before operation. It is concluded that midazolam (4 mg) is suitable to reduce the preoperative anxiety in patients who are to undergo minor gynecological surgery.