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Cowden's syndrome: a case report with clinical, histopathologic and immunological studies
A Saccardi1, S Bacci, P Romagnoli
1Department of Stomatology, University of Florence.
Abstract:
Cowden's syndrome is a rare autosomal dominant condition characterised by multiple hamartomas of the gastrointestinal tract and cancer of the breast and thyroid. We present a patient with multiple papillomatous lesions of the hard palate, facial papules, and a history of breast cancer and papillomas of the uterine cavity. We also report the results of light and electron microscopy of the palatal lesions and immunological studies of patient's T-lymphocyte function.
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