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Updated: Aug 19, 2026

Application of Long-term cultured Interferon-γ Enzyme-linked Immunospot Assay for Assessing Effector and Memory T Cell Responses in Cattle
Published on: July 11, 2015
[The T-cell response in parasitization by sheep bot (Oestrus ovis) larvae]
The kinetics of immunocompetent cells in sheep artificially infested with 80, 160, 1000 specimens of Oestrus ovis larvae and immunized with antigen from larvae protein was traced by stableons (E-REC) and antigen-fixing (Ag-REC) rosette formation reaction. It was found that E-REC level changes only a little in both infested and reinfested animals. Ag-REC kinetics mates with the rated larvae biomass changes in all age groups. Ag-REC level of infested animals is much higher and then regularly declines in the following cycles of invasion. T-lymphocytes level and death level of immunized lambs is much higher than in intact animals at the beginning of parasitism.
The kinetics of immunocompetent cells in sheep artificially infested with 80, 160, 1000 specimens of Oestrus ovis larvae and immunized with antigen from larvae protein was traced by stableons (E-REC) and antigen-fixing (Ag-REC) rosette formation reaction. It was found that E-REC level changes only a little in both infested and reinfested animals. Ag-REC kinetics mates with the rated larvae biomass changes in all age groups. Ag-REC level of infested animals is much higher and then regularly declines in the following cycles of invasion. T-lymphocytes level and death level of immunized lambs is much higher than in intact animals at the beginning of parasitism.
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