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The 5-amino-3-methyl-4-ureidoisoxazoles, synthesis and antileucemic activity
Die Pharmazie
|October 1, 1994
Abstract:
Some new substituted 5-amino-3-methyl-4-ureidoisoxazoles and the 4-ethyl urethane of the 5-amino-3-methyl-isoxazole have been synthesized from 5-amino-3-methyl-4-isoxazolecarboxylic acid azide. Some representative ureides with primary, secondary, and heterocyclic amines were tested for their antileucemic activity.