Related Experiment Videos
[Primary cardiac lymphoma with obstructive cardiac insufficiency]
M Giovannini1, P Monnier, A De Torrenté
1Institut neuchâtelois d'anatomie pathologique, Hôpital communal, La Chaux-de-Fonds.
Summary
A rare case of non-Hodgkin
Area of Science:
- Cardiology
- Oncology
- Pathology
Background:
- Congestive heart failure can have various underlying causes.
- Malignant lymphomas can rarely infiltrate cardiac structures.
Observation:
- An 80-year-old man presented with rapidly progressive congestive heart failure.
- Echocardiography revealed masses in the right atrium and ventricle.
- The patient's condition rapidly worsened, leading to death within two months.
Findings:
- Autopsy identified massive right-sided atrio-ventricular infiltration by malignant non-Hodgkin's lymphoma of the centroblastic type.
- The lymphoma caused subtotal obstruction of the tricuspid and pulmonary valves.
- Four intestinal metastases were found, with no other lymphoma manifestations.
Implications:
- This case highlights the importance of considering cardiac lymphoma in unexplained, rapidly progressive heart failure.
- Centroblastic lymphoma can present with cardiac involvement and valvular obstruction.
- The presence of isolated intestinal metastases alongside cardiac lymphoma is unusual.