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Gastro-duodenal bleeding after renal transplantation
Scandinavian Journal of Urology and Nephrology
|March 6, 1975
Summary
Gastro-duodenal complications like perforations and bleeding occurred in 10% of renal transplant patients. Prophylactic surgery significantly reduced these risks in patients with a history of gastro-duodenal issues.
Area of Science:
- Gastroenterology
- Nephrology
- Transplant Surgery
Background:
- Gastro-duodenal complications pose a significant risk following renal transplantation.
- A history of gastro-duodenal disorders increases the likelihood of these post-transplant complications.
Purpose of the Study:
- To evaluate the incidence and impact of gastro-duodenal complications in renal transplant recipients.
- To assess the efficacy of prophylactic surgery in mitigating these risks.
Main Methods:
- Retrospective analysis of 468 renal transplant patients from 1965-1974.
- Comparison of complication rates between patients with and without a history of gastro-duodenal disorders.
- Evaluation of outcomes following prophylactic gastric surgery.
Main Results:
- 10% of patients experienced gastro-duodenal perforations and/or significant bleedings.
- Half of these complications occurred in patients without prior gastro-duodenal history.
- Prophylactic surgery was well-tolerated and reduced complication frequency in predisposed patients.
Conclusions:
- Gastro-duodenal complications are a major hazard in renal transplant patients, particularly those with a prior history of ulcers.
- Prophylactic gastric surgery, when performed broadly before transplantation, can effectively eliminate this increased risk.