[Surface activity of blood during hemosorption]

Area of Science:

• Biophysics
• Hemoperfusion
• Surface Chemistry

Context:

• Hemosorption is a medical procedure involving blood purification.
• Understanding blood's surface properties during hemosorption is crucial for optimizing the process.
• Blood's behavior within sorption columns impacts treatment efficacy.

Purpose:

• To investigate the surface-active properties of blood during hemosorption.
• To analyze changes in blood's surface properties over time using (tau-S)-curves.
• To quantitatively compare blood isotherms before and after passage through a sorption column.

Summary:

• Blood samples were analyzed using (tau-S)-curves at different time points during hemosorption.
• The (tau-S)-curves exhibited a bend point, allowing for reconstruction and quantitative comparison of blood isotherms.
• Observed differences in isotherm parameters suggest changes in blood plasma composition and stable surface layer formation.

Impact:

• Provides insights into the dynamic changes in blood surface activity during hemosorption.
• The findings can inform the development of more effective hemosorption therapies.
• Contributes to understanding blood-plasma interactions within extracorporeal circuits.