Related Experiment Video

Updated: Aug 11, 2026

Advanced Confocal Microscopy Techniques to Study Protein-protein Interactions and Kinetics at DNA Lesions
12:43

Advanced Confocal Microscopy Techniques to Study Protein-protein Interactions and Kinetics at DNA Lesions

Published on: November 12, 2017

[Study of DNA-protein crosslinks induced by UV light in Hela cells]

G Ia Kolomiĭtseva, L P Kurochkina, E A Bobkova

    Biokhimiia (Moscow, Russia)
    |August 1, 1994
    PubMed

    More Related Videos

    Application of Laser Micro-irradiation for Examination of Single and Double Strand Break Repair in Mammalian Cells08:18

    Application of Laser Micro-irradiation for Examination of Single and Double Strand Break Repair in Mammalian Cells

    Published on: September 5, 2017

    Investigation of Protein Recruitment to DNA Lesions Using 405 Nm Laser Micro-irradiation12:29

    Investigation of Protein Recruitment to DNA Lesions Using 405 Nm Laser Micro-irradiation

    Published on: March 20, 2018

    Related Concept Videos

    Nucleotide Excision Repair01:08

    Nucleotide Excision Repair

    Overview
    Mutations01:35

    Mutations

    Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
    Chromosomal Alterations Are Large-Scale Mutations
    While point mutations are changes in a single nucleotide in...
    Nucleotide Excision Repair01:38

    Nucleotide Excision Repair

    DNA Distortion and Damage
    Cells are regularly exposed to mutagens—factors in the environment that can damage DNA and generate mutations. UV radiation is one of the most common mutagens and is estimated to introduce a significant number of changes in DNA. These include bends or kinks in the structure, which can block DNA replication or transcription. If these errors are not fixed, the damage can cause mutations, which in turn can result in cancer or disease depending on which sequences are...