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Hepatocellular-cholestatic liver injury due to amoxycillin-clavulanic acid combination
A Habior1, B Walewska-Zielecka, E Butruk
1Department of Gastroenterology, Medical Center for Postgraduate Education, Warsaw, Poland.
The Clinical Investigator
|August 1, 1994
Abstract:
Two cases (first cases from Poland and Eastern Europe) with liver injury due to amoxycillin-clavulanic acid (augmentin) are reported. Pruritus and jaundice were the main symptoms. Liver biopsy revealed mixed hepatocellular-cholestatic liver injury in both cases. In addition, in one case the microgranulomalike aggregate of inflammatory cells was found. Clinical and laboratory abnormalities returned to normal within 13 weeks.