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IFN-gamma-stimulated human vascular endothelial cells function as accessory cells for superantigen-induced TNF

K Imanishi1, H Akatsuka, K Inada

  • 1Department of Microbiology and Immunology, Tokyo Women's Medical College, Japan.

In the presence of IFN-gamma-stimulated vascular endothelial cells which have acquired HLA class II molecules, T cells produced tumor necrosis factors (TNF-alpha and TNF-beta) and IL-2 in response to stimulation with streptococcal pyrogenic exotoxin A.

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