Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Human protothecosis and environment]

M Huerre1, P Ravisse, H Solomon

  • 1Unité d'Histopathologie, Institut Pasteur, Paris.

Bulletin De La Societe De Pathologie Exotique (1990)
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Canadian Surgery Forum 2018: St. John's, NL Sept. 13-15, 2018.

Canadian journal of surgery. Journal canadien de chirurgie·2022
Same author

Yeast tissue phase of Emmonsia pasteuriana inoculated in golden hamster by intratesticular way.

Mycoses·2017
Same author

[A lumbar vertebral eosinophilic granuloma with spinal instability in an adolescent].

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2017
Same author

Colonization with Helicobacter is concomitant with modified gut microbiota and drastic failure of the immune control of Mycobacterium tuberculosis.

Mucosal immunology·2017
Same author

Novel p53 target genes secreted by the liver are involved in non-cell-autonomous regulation.

Cell death and differentiation·2015
Same author

[Performance of prenatal diagnosis and postnatal development of congenital lung malformations].

Gynecologie, obstetrique & fertilite·2015
Same journal

Bulletin de la Societe de pathologie exotique (1990)·2024
Same journal

Bulletin de la Societe de pathologie exotique (1990)·2024
Same journal

[3rd Day Dedicated to the Scientific Works of Young Doctors in French Guiana: "Our Residents Got Talent" - 5th December 2019, université de Guyane, Cayenne, French Guiana].

Bulletin de la Societe de pathologie exotique (1990)·2021
Same journal

[Practices and Factors Associated with Recent HIV Testing in the General Population, Côte d'Ivoire: Results of the ANRS Study 12323 DOD-CI].

Bulletin de la Societe de pathologie exotique (1990)·2021
Same journal

[Sexual Behaviours at Risk of HIV Infection among Male to Female Transgender People in Benin].

Bulletin de la Societe de pathologie exotique (1990)·2021
Same journal

[Contribution of Real-Time PCR in the Diagnosis of Cutaneous Leishmaniasis: Experience of the Pasteur Institute of Tunis].

Bulletin de la Societe de pathologie exotique (1990)·2021
See all related articles

Protothecosis, caused by achlorophylous algae Prototheca, presents as uncommon cutaneous or systemic infections, often diagnosed via histology. These opportunistic agents are ubiquitous in sewage and transmitted through inoculation.

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Dermatology

Background:

  • Protothecosis is an uncommon infection caused by Prototheca, a type of achlorophylous alga.
  • Since 1964, approximately 80 human cases have been documented globally, with a notable cluster in the Southeastern United States.
  • The condition can manifest as cutaneous lesions, olecranon bursitis, or systemic disease, often associated with immunosuppression.

Purpose of the Study:

  • To review the clinical manifestations, diagnosis, and ecology of Protothecosis.
  • To highlight the diagnostic features of Prototheca in tissue samples.
  • To discuss the environmental sources and transmission routes of Prototheca.

Main Methods:

  • Literature review of reported human cases of Protothecosis.

Related Experiment Videos

  • Histopathological analysis of tissue samples to identify Prototheca morphology.
  • Ecological studies on the prevalence and habitats of Prototheca species.

    • Main Results:

    • Clinical presentations include cutaneous lesions (papules, plaques, eczematoid), olecranon bursitis (25% of cases), and systemic infections.
    • Diagnosis is frequently made by histology, revealing granulomas with endospores and characteristic morula-like sporangia of Prototheca wickerhamii.
    • Prototheca are ubiquitous in sewage and aquatic environments, transmitted via traumatic inoculation, and are considered opportunistic pathogens.

    Conclusions:

    • Protothecosis is a rare opportunistic infection with diverse clinical presentations.
    • Histopathology is crucial for diagnosis, identifying characteristic Prototheca structures.
    • Understanding Prototheca's ecology and transmission is vital for prevention and management.