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SCP application or B15 stimulation activates cAPK in the ARC muscle of Aplysia
S L Hooper1, W C Probst, E C Cropper
1Department of Biological Sciences, Ohio University, Athens 45701.
Brain Research
|September 19, 1994
Abstract:
Application of small cardioactive peptide (SCP) or stimulation of motorneuron B15 increases the level of activated cAMP-dependent protein kinase (cAPK) in the ARC muscle. SCP application also appears to induce a translocation of cAPK between different subcellular compartments of the ARC muscle and this translocation is also induced by cAMP addition to muscle homogenates. These results suggest that the actions of SCP in the Aplysia ARC neuromuscular system are mediated via the cAPK signal transduction pathway.