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Nuclear bodies associated with core particles of hepatitis B virus in a healthy carrier
N Makarova1, G Pasquinelli, G N Martinelli
1Latvian Medical Academy, Riga.
Abstract:
An unusual association of nuclear bodies (NB) with core particles of hepatitis B virus (HBV) is described in a healthy carrier who histologically showed ground glass hepatocytes with occasional sanded-nuclei. Ultrastructurally, many hepatocytes had typical features of HBV infection. Unexpectedly, a few cells contained previously undescribed complexes of NB studded with a number of HBV core particles. The ultrastructural characteristics of these complexes and their possible relation to HBV morphogenesis are briefly discussed.
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