Psychogenic seizures in children: long-term analysis of 43 cases

M E Lancman1, J J Asconapé, S Graves

  • 1Department of Neurology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC 27157.

Insights

This study examined psychogenic seizures in 43 children and adolescents. Findings indicate significant distress and quality of life impacts, with no clear predictors for seizure outcomes.

Area of Science:

  • Neurology
  • Pediatrics
  • Psychiatry

Background:

  • Psychogenic seizures, also known as non-epileptic seizures, often begin in childhood or adolescence.
  • Understanding the clinical characteristics and impact of these seizures is crucial for effective management.

Purpose of the Study:

  • To investigate the clinical features, associated distress, and quality of life in pediatric patients with psychogenic seizures.
  • To identify potential predictors of clinical outcomes in this population.

Main Methods:

  • Retrospective study of 43 patients with psychogenic seizures onset before age 16.
  • Utilized electroencephalography (EEG) and video-EEG monitoring for diagnosis.
  • Assessed clinical seizure characteristics, neuropsychological function, and patient/family distress.

Main Results:

  • The study included 32 females and 11 males, with a mean age of onset at 12.4 years.
  • Common seizure features included unresponsiveness with violent movements or generalized trembling.
  • Significant personal and family distress was reported, impacting quality of life, with no statistically significant predictors of outcome identified.

Conclusions:

  • Psychogenic seizures in pediatric patients are associated with considerable distress and reduced quality of life.
  • Clinical presentation is variable, and current diagnostic methods did not reveal significant predictors for long-term outcomes.
  • Further research is needed to identify prognostic factors and optimize treatment strategies.

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