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Primary vesicoureteric reflux in Thai children with urinary tract infection
C Tapaneya-Olarn1, W Tapaneya-Olarn, S Tunlayadechananont
1Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Insights
Genitourinary (GU) anomalies are common in pediatric patients, with primary vesicoureteral reflux (VUR) being the most frequent. While low-grade VUR often resolves spontaneously, high-grade VUR may require intervention but can still lead to lasting kidney damage.
Area of Science:
- Pediatric Urology
- Nephrology
- Medical Imaging
Background:
- Genitourinary (GU) anomalies are a significant concern in pediatric populations.
- Primary vesicoureteral reflux (VUR) is a common GU anomaly requiring investigation.
- Understanding the prevalence and outcomes of GU anomalies is crucial for patient management.
Purpose of the Study:
- To retrospectively analyze the prevalence of GU anomalies in pediatric patients.
- To specifically investigate the incidence and characteristics of primary VUR.
- To evaluate the factors influencing VUR resolution and long-term outcomes.
Main Methods:
- Retrospective analysis of 443 pediatric patients.
- Detailed investigation for genitourinary anomalies, focusing on primary VUR.
- Correlation of VUR grade with spontaneous resolution and infection control.
Main Results:
- Genitourinary anomalies were identified in 46% of patients.
- Primary VUR was present in 29% of patients with GU anomalies, making it the most common.
- GU anomalies were more prevalent in younger males and older females.
- Low to medium grade VUR showed spontaneous resolution, linked to infection control.
- High grade VUR had limited spontaneous resolution, and surgery did not prevent damage progression.
Conclusions:
- Primary VUR is the most frequent genitourinary anomaly in pediatric patients.
- VUR grade significantly impacts spontaneous resolution and potential for kidney damage.
- Early detection and management of VUR are essential to prevent long-term renal sequelae.
Abstract:
Four hundred and forty-three pediatric patients were analysed retrospectively for GU anomalies especially for primary VUR. Genito urinary tract anomalies were found in 46 per cent of investigated patients. Primary VUR was found in 29 per cent of patients who had GU anomalies and were the most common anomalies found. The GU anomalies were found more in younger males, and older females. Low to medium grade VUR tended to have spontaneous resolution and correlated well with degrees of controlling infection. In high grade VUR, fewer patients may have spontaneous resolution, surgery can correct the reflux but not the progression of the damage.