[Hemodynamic and cerebrospinal fluid dynamic changes in acute brain prolapse]

Experiments on 19 mongrel dogs were made to examine hemo- and liquorodynamic changes in acute brain prolapse. It was found that irritation of the hypothalamic region resulted in elevated intracranial, sagittal sinus, systemic arterial and venous pressures. The rate of cerebrospinal fluid production in acute brain prolapse increased four-fold as compared with the baseline values. It is concluded that in acute brain prolapse, increased cerebrospinal production rate and enhanced brain blood filling led to intracranial decompensation.