[Changes in lipid peroxidation and phospholipid spectrum of blood in patients with lung cancer]

The parameters of the lipid peroxidation - antioxidants system, phospholipid profile, erythrocytes and blood plasma of 47 patients with lung cancer were studied. Serious disturbances in phospholipids profile in cases of central and peripheral lung cancer were identified. They included a decreased phosphatidycholine level, accumulation of lysophospholipids and appearance of phosphatidyglyceral fraction in blood plasma. Those shifts occurred alongside with enhanced lipid peroxidation and a deficit of antioxidation protection factors.