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Conformation therapy using a computer controlled telecobalt unit for advanced cervical carcinoma
L F Senanayake1, S L Sun, C Collis
1Department of Radiotherapy and Oncology, Royal Free Hospital, London, UK.
Clinical Oncology (Royal College of Radiologists (Great Britain))
|January 1, 1994
Summary
Conformation radiotherapy effectively treated advanced cervical cancer with para-aortic node metastases. This advanced radiotherapy technique showed encouraging survival rates and minimal complications in patients.
Area of Science:
- Oncology
- Radiation Oncology
Background:
- Advanced cervical carcinoma frequently presents with common iliac/para-aortic node metastases.
- Effective treatment of these advanced cases requires targeting a large irradiation volume.
Purpose of the Study:
- To evaluate the efficacy and toxicity of conformation radiotherapy for advanced cervical carcinoma with common iliac/para-aortic node metastases.
Main Methods:
- Retrospective analysis of 16 patients treated between 1980 and 1987.
- Conformation radiotherapy delivered 5000-5500 cGy to a large volume (L1/L2 to pelvis) using a computer-controlled tracking cobalt unit.
- Concurrent or prior treatments included surgery, chemotherapy, and brachytherapy.
Main Results:
- Actuarial survival rates at 1, 3, and 5 years were 81%, 44%, and 37%, respectively.
- Locoregional control rate was 62.5%.
- No para-aortic node relapses were observed, and the treatment was well-tolerated with no severe acute or delayed radiation complications.
Conclusions:
- Conformation radiotherapy, encompassing pelvic and para-aortic nodes, is an effective treatment for advanced cervical cancer.
- This technique demonstrates minimal morbidity and encourages survival outcomes in patients with node-positive advanced cervical carcinoma.