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Related Experiment Videos

Migraine, polycythemia and chronic mountain sickness

A Arregui1, F León-Velarde, J Cabrera

  • 1Department of Neurology and Physiological Sciences, Universidad Peruana Cayetano Heredia, Lima, Peru.

Cephalalgia : an International Journal of Headache
|October 1, 1994
PubMed
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High altitude living is linked to increased headache prevalence, particularly migraine with aura. Migraineurs at high altitudes exhibit higher hemoglobin and chronic mountain sickness scores, suggesting a connection between headaches and altitude-related physiological changes.

Area of Science:

  • Altitude Medicine
  • Epidemiology
  • Neurology

Background:

  • High altitude environments present unique physiological challenges.
  • Headache disorders are common globally, but their prevalence at extreme altitudes is less understood.
  • Chronic mountain sickness is a known condition at high altitudes.

Purpose of the Study:

  • To determine the prevalence of headache disorders in adult men residing at high altitude (4300 meters).
  • To investigate the relationship between headache types, age, and physiological markers associated with high altitude.
  • To explore potential links between migraine, tension-type headaches, and chronic mountain sickness indicators.

Main Methods:

  • Epidemiological study involving 379 adult men permanently residing at 4300 meters.

Related Experiment Videos

  • Assessment of headache prevalence (migraine, tension-type, other) and headache frequency.
  • Measurement of hemoglobin levels, oxygen saturation, and chronic mountain sickness scores.
  • Analysis of age-specific trends in headache frequency and physiological parameters.

    • Main Results:

    • Prevalence: 32.2% migraine (primarily migraine with aura), 15.2% tension-type headache, 7.2% other headaches.
    • Migraine and episodic tension-type headache frequencies increased with age (20-59 years).
    • Higher hemoglobin, lower oxygen saturation, and elevated chronic mountain sickness scores were age-specifically increased.
    • Male migraineurs and those with frequent headaches (>2/month) showed the highest hemoglobin and chronic mountain sickness scores compared to non-headache sufferers.

    Conclusions:

    • Headache disorders, especially migraine, are prevalent in high-altitude populations.
    • Age-related increases in headache frequency correlate with altitude-related physiological changes.
    • Migraine and frequent headaches at high altitude are associated with higher hemoglobin levels and chronic mountain sickness, suggesting a potential pathophysiological link.