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Severe inflammatory upper airway stenosis in ulcerative colitis

H Rickli¹, C Fretz, M Hoffman

¹Dept of Medicine, Kantonsspital St. Gallen, Switzerland.

The European Respiratory Journal

|October 1, 1994

Summary

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This case study highlights severe upper airway stenosis in a patient with ulcerative colitis. Prompt corticosteroid treatment effectively resolved the airway obstruction, demonstrating a crucial link between inflammatory bowel disease and respiratory complications.

Area of Science:

Pulmonology
Gastroenterology
Otolaryngology

Background:

Ulcerative colitis (UC) is an inflammatory bowel disease frequently associated with extraintestinal manifestations.
Respiratory involvement in UC typically presents as chronic bronchitis or bronchiectasis.
Laryngeal and large airway stenosis are rare but significant complications.

Observation:

A 23-year-old woman with a history of ulcerative colitis developed progressive hoarseness, cough, and dyspnea.
Symptoms worsened, leading to dysphagia and severe upper airway obstruction due to glottic stenosis.
Inflammatory swellings were identified as the cause of the glottic narrowing.

Findings:

Systemic corticosteroid therapy resulted in rapid clinical improvement.

Related Experiment Videos

Normal airway patency was restored within a few months of treatment.

This case confirms that UC-related inflammation can affect the larynx and large airways.

Implications:

Highlights the importance of considering airway complications in ulcerative colitis patients with respiratory symptoms.
Emphasizes the efficacy of systemic corticosteroids in managing severe laryngeal stenosis secondary to inflammatory bowel disease.
Suggests that a multidisciplinary approach involving pulmonologists, gastroenterologists, and otolaryngologists may be beneficial for such cases.