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Pseudomyxoma peritonei: a report of eight cases
S Sudhindran1, C J Varghese, H Ramesh
1Department of Gastroenterology, Deva Matha Hospital, Koothattukulam, Kerala.
Objective:
To assess the effectiveness of surgical treatment for pseudomyxoma peritonei.
Design:
Retrospective analysis.
Setting:
Referral center.
Patients:
Eight patients with pseudomyxoma peritonei, five with mucinous tumors of the ovary and three with mucoceles of the appendix.
Intervention:
All patients underwent cytoreductive surgery with removal of source i.e. panhysterectomy with appendicectomy in 5 and appendicectomy in 3. Systemic chemotherapy was used in 6 and systemic plus intraperitoneal chemotherapy in one case.
Results:
Over 18 to 86 months' follow up, two patients died (at 18 and 24 mo) and 2 are alive with recurrence. Recurrence occurred only in those with inadequate clearance of mucinous material at the initial operation. The remaining 4 patients are free of disease.
Conclusion:
Aggressive surgical therapy with-chemotherapy is effective in providing long-term relief or cure in pseudomyxoma peritonei.