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Mycotic aneurysms of the intracranial vessels

V V Radhakrishnan1, A Saraswathy, D Rout

  • 1Department of Pathology, Sree Chitra Tirunal Institute for Medical Sciences & Technology, Thiruvananthapuram.

The Indian Journal of Medical Research
|November 1, 1994
PubMed

Insights

This study reports on Aspergillus cerebral aneurysms in young women following surgery. Iatrogenic factors may play a role in the development of these serious fungal brain infections.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Vascular Surgery

Background:

  • Cerebral aneurysms are abnormal bulges in brain blood vessels.
  • Aspergillus infections can affect various organs, including the brain.
  • Post-surgical complications require thorough investigation.

Purpose of the Study:

  • To describe the clinical and pathological features of Aspergillus cerebral aneurysms.
  • To investigate the potential link between intra-abdominal surgery under spinal anesthesia and these aneurysms.
  • To highlight the role of iatrogenic factors in the pathogenesis.

Main Methods:

  • Case series reporting on four young women.
  • Clinical presentation analysis.
  • Pathological examination of cerebral vasculature.

Main Results:

  • Four young women developed meningitis symptoms 7-16 days post-operatively.
  • Ruptured aneurysms were found in the basilar artery and its branches within the circle of Willis.
  • Aspergillus was identified as the causative agent.

Conclusions:

  • Aspergillus cerebral aneurysms are a rare but severe complication.
  • Iatrogenic factors related to surgery and anesthesia may contribute to their development.
  • Early recognition and understanding of pathogenesis are crucial for patient outcomes.

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