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Updated: Aug 19, 2026

Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
In vitro biomechanical evaluation of anterior cruciate ligament graft substitutes
1Civil Engineering Department, Osmania University, Hyderabad.
Abstract:
The study was undertaken to identify an isoelastic graft material for the anterior cruciate ligament (ACL). Double transducer ultrasonic pulse transmission method was employed for determining the elastic properties of normal ACL in comparison with various graft materials like the central third of the patellar tendon, semitendinosus and iliotibial band in different twisted forms. The elasticity and rigidity parameters were studied by taking ACL as being equal to 100 per cent. Our results indicated that the strength of the graft depended upon the density of the collagen bundles and elastic properties depended upon the pretensioning of the graft.

