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Pustular vasculitis of the hands

G Strutton1, D Weedon, I Robertson

  • 1Department of Pathology, Princess Alexandra Hospital, Woolloongabba, Brisbane, Australia.

Journal of the American Academy of Dermatology
|February 1, 1995
PubMed
Summary

A distinct skin condition, termed pustular vasculitis of the hands, presents as a hand eruption resembling Sweet's syndrome but characterized by leukocytoclastic vasculitis. This condition rapidly responds to prednisone treatment.

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Area of Science:

  • Dermatology
  • Pathology
  • Rheumatology

Background:

  • A unique cutaneous eruption affecting the hands and fingers was observed.
  • Clinical presentation mimicked Sweet's syndrome, but histological examination revealed severe leukocytoclastic vasculitis.

Observation:

  • Six female patients (ages 41-79) presented with a symmetric eruption on the dorsal radial aspects of hands and digits.
  • Lesions manifested as papules and plaques, accompanied by fever and leukocytosis.

Findings:

  • Histopathology confirmed severe leukocytoclastic vasculitis.
  • The eruption showed no response to antibiotics but a rapid positive response to prednisone therapy.

Implications:

  • This study identifies and characterizes a distinct dermatological entity: pustular vasculitis of the hands.
  • Recognition of this condition is crucial for appropriate diagnosis and treatment, differentiating it from similar-appearing dermatoses.

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