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Glutamine metabolism and utilization: relevance to major problems in health care
B Moskovitz1, Y Katz, P Singer
1Department of Urology, Bnai Zion Medical Center, Haifa, Israel.
Pharmacological Research
|July 1, 1994
Abstract:
Glutamine plays an important role in normal and pathophysiological states. In this review we describe the biochemical synthesis and degradation pathways of glutamine, as well as its utilization by the immune system and in rapidly dividing cells. Also discussed are glutamine behaviour in catabolic states and the therapeutic implications of this amino acid in total parenteral nutrition, digestive diseases and cancer.