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Hyperaggregation of platelets in intestinal tuberculosis: role of platelets in chronic inflammation
R Sarode1, D Bhasin, N Marwaha
1Department of Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
American Journal of Hematology
|January 1, 1995
Abstract:
Eighty-eight percent (38/43) patients of intestinal tuberculosis showed significant hyperaggregation of platelets (P < 0.001). Serum and plasma from 15 patients when incubated with normal platelets caused hyperaggregation. Gel filtered platelets from 2 patients suspended in normal plasma showed hyperaggregation of platelets with arachidonic acid. Tubercular protein had no effect on platelet aggregation. A role of hyperactive platelets in chronic inflammatory response is discussed.