Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Initial experience with laparoscopic Nissen fundoplication

C M Ferguson1, D W Rattner

  • 1Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston.

The American Surgeon
|January 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Standardised survey method for identifying catchment risks to water quality.

Journal of water and health·2016
Same author

Reduced response of human meniscal cells to Osteogenic Protein 1 during osteoarthritis and pro-inflammatory stimulation.

Osteoarthritis and cartilage·2016
Same author

Osteoarthritic changes in vervet monkey knees correlate with meniscus degradation and increased matrix metalloproteinase and cytokine secretion.

Osteoarthritis and cartilage·2015
Same author

Pro-inflammatory stimulation of meniscus cells increases production of matrix metalloproteinases and additional catabolic factors involved in osteoarthritis pathogenesis.

Osteoarthritis and cartilage·2013
Same author

Biosafety testing of genetically modified ryegrass (Lolium perenne) using a model for the optimum selection of test invertebrates.

Environmental entomology·2013
Same author

Histopathology of naturally occurring and surgically induced osteoarthritis in mice.

Osteoarthritis and cartilage·2012
Same journal

Complete Response of Merkel Cell Carcinoma to Immunotherapy and Single-Fraction Radiotherapy Following Severe COVID-19 Infection: A Case Report and Review of Immune Mechanism.

The American surgeon·2026
Same journal

Perioperative Acute Myocardial Infarction in Non-Cardiac Operations: A National Analysis.

The American surgeon·2026
Same journal

Outcomes of Completion Cholecystectomy: Association With Patient Comorbidity in a National Database.

The American surgeon·2026
Same journal

Building the Conversation: Editorial Stewardship in Contemporary Surgical Publishing.

The American surgeon·2026
Same journal

Musculoskeletal Pain in Surgeons on Operating Days.

The American surgeon·2026
Same journal

Splenectomy During Cytoreductive Surgery: Marker of Surgical Burden or Independent Predictor of Morbidity?

The American surgeon·2026
See all related articles

Laparoscopic Nissen fundoplication is a viable surgical option for gastroesophageal reflux disease, offering rapid recovery. However, this complex procedure can be time-consuming and has a short-term recurrence rate.

Area of Science:

  • Gastroenterology
  • Minimally Invasive Surgery
  • Surgical Techniques

Background:

  • Gastroesophageal reflux disease (GERD) significantly impacts patient quality of life.
  • Medical therapy is often insufficient for severe or refractory GERD.
  • Classic Nissen fundoplication is a standard surgical treatment for GERD.

Purpose of the Study:

  • To evaluate the feasibility and outcomes of laparoscopic Nissen fundoplication.
  • To assess the safety and efficacy of this minimally invasive approach for GERD.

Main Methods:

  • Sixteen adult patients with documented GERD underwent laparoscopic Nissen fundoplication.
  • Procedures involved gastric fundal dissection, division of short gastric vessels, crural approximation, and a loose fundoplication over a dilator.

Related Experiment Videos

  • Data collected included operative time, complications, recovery, and symptom recurrence.

    • Main Results:

    • Fifteen of 16 procedures were completed laparoscopically; one conversion to open surgery was needed due to bleeding.
    • Average operative time was 180 minutes; patients were discharged within 4.1 days.
    • Short-term follow-up showed 14 of 15 patients were free of reflux symptoms, with a 6% recurrence rate. Five patients experienced postoperative dysphagia.

    Conclusions:

    • Standard Nissen fundoplication can be successfully performed laparoscopically, enabling rapid patient recovery.
    • The laparoscopic approach is technically demanding and associated with a notable short-term symptom recurrence rate.