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Role of nitric oxide in brain ischemia
S Sato1, T Tominaga, T Ohnishi
1Philadelphia Biomedical Research Institute, King of Prussia, Pennsylvania 19406.
Annals of the New York Academy of Sciences
|November 17, 1994
Abstract:
In order to study the role of nitric oxide (NO) in rat brain ischemia, an in vivo spin trapping technique was applied. The results showed that NO was produced not only during ischemia but also during reperfusion. The role of NO production during ischemia may be to increase cerebral blood flow. The NO production during reperfusion seems to be related to tissue damage.