Cerebral thromboembolic complications associated with the use of a nonionic contrast medium in coronary angiography

K Levorstad1, K Vatne, U Brodahl

  • 1Department of Diagnostic Radiology, National Hospital, University of Oslo, Norway.

Insights

Cerebrovascular complications occurred in 0.21% of patients undergoing coronary angiography. After excluding high-risk individuals, the incidence of cerebral thromboembolic events was 0.10%, highlighting the importance of procedural precautions.

Area of Science:

  • Cardiology
  • Neurology
  • Radiology

Background:

  • Coronary angiography is a common procedure.
  • Cerebrovascular complications are a potential risk.
  • Nonionic contrast media like iohexol are frequently used.

Purpose of the Study:

  • To determine the incidence of cerebrovascular complications during coronary angiography.
  • To assess the role of the nonionic contrast medium iohexol in these events.
  • To identify risk factors and preventive measures.

Main Methods:

  • Retrospective analysis of 5,339 patients undergoing coronary angiography.
  • Use of nonionic contrast medium iohexol (Omnipaque).
  • Identification and exclusion of patients with predisposing conditions for thromboembolism.

Main Results:

  • 11 patients (0.21%) experienced cerebrovascular complications.
  • Six patients had predisposing conditions; 3 had prior stroke symptoms.
  • Excluding these 6, the incidence of cerebral thromboembolic events was 0.10%.

Conclusions:

  • Cerebrovascular complications are rare during coronary angiography with iohexol.
  • Precise catheterization technique and anticoagulation/antiplatelet therapy are crucial for prevention.
  • The specific role of iohexol in these complications requires further investigation.

Related Concept Videos

Radiological Investigation I: X-ray and CT01:30

Radiological Investigation I: X-ray and CT

Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and the...
Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
Cardiac Catheterization I: Pre-Procedure Overview01:28

Cardiac Catheterization I: Pre-Procedure Overview

Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...