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Updated: Aug 16, 2026

Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic Poly(I:C)
07:13

Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic Poly(I:C)

Published on: March 25, 2016

[A longitudinal study on maternal-fetal transfer of antibody against poliomyelitis]

E You1, Q Yang, Q L Yang

  • 1Disease Prevention Center, Dong-feng Motor Corporation, Shi Yan.

Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi
|June 1, 1994
PubMed

A study on antibody distribution and titer against poliovirus in 67 mothers and their 60-day-old new-born babies was carried out in Shi-yan, Hubei Province. The positive rates and the geometric mean titers of antibodies against Types I-II poliovirus in mothers were 98.58%, 1:32.67; 95.5%, 1:30.07; 92.5%, 1:14.58, respectively. In their 60-day-old babies, the antibody positive rates and geometric mean titers fell obviously: they were 34.3%, 1:2.45; 34.3%, 1:2.22; and 14.9%, 1:1.34, respectively. The authors suggest to immune those neonates (OPV zero), or to immune those mothers beginning from 28 weeks of pregnancy in order to raise the antibody titer and protect their babies during the early days.

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