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Clostridium perfringens endophthalmitis
A M Abu el-Asrar1, K F Tabbara
1Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Abstract:
Our report describes a 35 year-old male who sustained a penetrating injury with an intraocular foreign body and developed endophthalmitis. Gram stain showed Gram positive bacilli and culture grew Clostridium perfringens. The patient was managed successfully by therapeutic vitrectomy and intravitreal and systemic antibiotic therapy. Early vitrectomy and intravitreal antibiotics should be considered in patients who develop severe endophthalmitis following penetrating injury.
Insights
A penetrating eye injury led to severe endophthalmitis caused by Clostridium perfringens. Prompt therapeutic vitrectomy and antibiotic treatment successfully managed the infection.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Penetrating ocular trauma can lead to severe intraocular infections.
- Endophthalmitis, an inflammation of the eye's interior, poses a significant risk after penetrating injuries.
Observation:
- A 35-year-old male presented with endophthalmitis following a penetrating eye injury with an intraocular foreign body.
- Gram stain revealed Gram-positive bacilli, and cultures identified Clostridium perfringens as the causative agent.
Findings:
- The patient received successful management through therapeutic vitrectomy and a combination of intravitreal and systemic antibiotic therapy.
- Clostridium perfringens was identified as the pathogen responsible for the severe endophthalmitis.
Implications:
- Early surgical intervention, specifically therapeutic vitrectomy, is crucial for managing severe endophthalmitis post-penetrating injury.
- The administration of intravitreal antibiotics alongside systemic therapy is a key component in the successful treatment of such cases.