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Clostridium perfringens endophthalmitis
A M Abu el-Asrar1, K F Tabbara
1Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Documenta Ophthalmologica. Advances in Ophthalmology
|January 1, 1994
Summary
A penetrating eye injury led to severe endophthalmitis caused by Clostridium perfringens. Prompt therapeutic vitrectomy and antibiotic treatment successfully managed the infection.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Penetrating ocular trauma can lead to severe intraocular infections.
- Endophthalmitis, an inflammation of the eye's interior, poses a significant risk after penetrating injuries.
Observation:
- A 35-year-old male presented with endophthalmitis following a penetrating eye injury with an intraocular foreign body.
- Gram stain revealed Gram-positive bacilli, and cultures identified Clostridium perfringens as the causative agent.
Findings:
- The patient received successful management through therapeutic vitrectomy and a combination of intravitreal and systemic antibiotic therapy.
- Clostridium perfringens was identified as the pathogen responsible for the severe endophthalmitis.
Implications:
- Early surgical intervention, specifically therapeutic vitrectomy, is crucial for managing severe endophthalmitis post-penetrating injury.
- The administration of intravitreal antibiotics alongside systemic therapy is a key component in the successful treatment of such cases.