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Regulated expression of the histidase structural gene in Streptomyces griseus
P C Wu1, K V Srinivasan, K E Kendrick
1Department of Microbiology, Ohio State University, Columbus 43210.
Journal of Bacteriology
|February 1, 1995
Abstract:
The histidase structural gene from Streptomyces griseus was expressed from a leaderless, monocistronic transcript. Multiple copies of the DNA located upstream of the hutH transcription initiation site led to a significant level of histidase activity when present in trans in the wild-type strain grown under noninducing conditions.