Neonatal hypocalcemia: to treat or not to treat? (A review)

The various definitions of neonatal hypocalcemia (NHC) are critically examined. The authors review the known and less known complications of NHC and of its treatment. They emphasize the need for a definition of NHC in terms of serum ionized rather than total calcium concentrations, the rationale for treating symptomatic NHC, as well as the need for further research in infants with asymptomatic NHC.