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Related Experiment Videos

[Ginkgo--myth and reality]

A Z'Brun1

  • 1Medizinische Klinik, Kantonsspital Luzern.

Praxis
|January 3, 1995
PubMed
Summary

Ginkgo biloba extracts, containing flavonoids and terpenes, effectively treat cerebral insufficiency and peripheral artery disease. Clinical studies confirm significant improvements in these conditions using specific extracts like EGb 761.

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Area of Science:

  • Pharmacology
  • Herbal Medicine
  • Clinical Research

Background:

  • Ginkgo biloba, an ancient plant, has leaf extracts used traditionally and in modern Western medicine since the 1960s.
  • Key pharmacologically active compounds include flavonoids (antioxidants) and terpenes like ginkgolides (platelet-activating factor inhibitors).

Purpose of the Study:

  • To review the clinical significance and efficacy of Ginkgo biloba extracts.
  • To highlight indications for Ginkgo biloba, focusing on cerebral insufficiency and peripheral artery disease.

Main Methods:

  • Review of placebo-controlled clinical studies.
  • Analysis of investigations on specific Ginkgo biloba extracts, such as EGb 761 and LI 1370.

Main Results:

  • Ginkgo biloba extracts have demonstrated significant and effective influence on symptoms of cerebral insufficiency.
  • The compounds act as oxygen-free radical scavengers and specific platelet-activating factor inhibitors.

Conclusions:

  • Ginkgo biloba extracts are clinically indicated for cerebral insufficiency and moderate peripheral atherosclerotic disease.
  • Evidence supports the efficacy of specific extracts like EGb 761 in managing these conditions.

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