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Clinical presentation of atopic dermatitis in Negroid children
W M Macharia1, G M Anabwani, D M Owili
1Department of Paediatrics, University of Nairobi, Kenya.
Insights
Clinical findings in Negroid children with atopic dermatitis (AD) show similar presentation to white children. Early onset and facial/flexural involvement are common in pediatric AD.
Area of Science:
- Pediatric Dermatology
- Clinical Immunology
Background:
- Atopic dermatitis (AD) is a common chronic inflammatory skin condition.
- Understanding AD clinical presentation in diverse populations is crucial for accurate diagnosis and management.
Purpose of the Study:
- To describe the clinical findings of atopic dermatitis in a cohort of 54 Negroid children.
- To compare the clinical presentation of AD in Negroid children with that reported in white children.
Main Methods:
- Retrospective analysis of clinical data from 54 Negroid children diagnosed with atopic dermatitis.
- Data collected included age at onset, sex ratio, age range, and specific clinical manifestations.
Main Results:
- The study included 54 Negroid children aged 0.25 to 10.25 years, with a male to female ratio of 1.2:1.
- Onset before age 1 year occurred in 81.1% of cases. Facial and flexural involvement were noted in 81.5% and 70.4% of patients, respectively.
- Associated conditions included keratosis pilaris (72%), recurrent skin infections (45%), ichthyosis (40%), and allergic conjunctivitis (11.8%).
Conclusions:
- The clinical presentation of atopic dermatitis in Negroid children is largely similar to that observed in white children.
- Early onset and characteristic skin involvements are key features of pediatric AD in this population.
Abstract:
Clinical findings in 54 consecutive negroid children with atopic dermatitis (AD) are presented. The age range was 0.25 to 10.25 years. Male:Female ratio was 1.2:1. Time of onset range between 1 week and 8 years with onset before the age of 1 year in 81.1%. Facial and flexural involvement were observed in 81.5% and 70.4% of patients respectively. The latter was more common after the age of two years. Keratosis pilaris, repeated skin infections and ichthyosis were observed in 72, 45, and 40 per cent of the children. Allergic conjunctivitis was present in 11.8%. The findings suggest that the clinical presentation of AD in Negroid children is similar to that in white children.