Related Experiment Videos
Azole resistance in oropharyngeal Candida albicans strains isolated from patients infected with human
X He1, R N Tiballi, L T Zarins
1Department of Internal Medicine, University of Michigan Medical School, Ann Arbor.
Antimicrobial Agents and Chemotherapy
|October 1, 1994
Abstract:
For 212 oropharyngeal isolates of Candida albicans, the fluconazole MICs for 50 and 90% of strains tested were 0.5 and 16 micrograms/ml, respectively, and those of itraconazole were 0.05 and 0.2 micrograms/ml, respectively. Of 16 isolates for which fluconazole MICs were > 64 micrograms/ml, itraconazole MICs for 14 were < or = 0.8 micrograms/ml and for 2 were > 6.4 micrograms/ml. Most fluconazole-resistant strains remained susceptible to itraconazole; whether itraconazole will prove effective for refractory thrush remains to be shown.