Endotoxin inhibits glucuronidation in the liver. An effect mediated by intercellular communication

G Bánhegyi1, I Mucha, T Garzó

  • 11st Institute of Biochemistry, Semmelweis University of Medicine, Budapest, Hungary.

Biochemical Pharmacology
|January 6, 1995
PubMed
Summary

Endotoxin (lipopolysaccharide) impairs liver glucuronidation, an effect preventable by cyclooxygenase inhibitors. This suggests endotoxin-induced inhibition is mediated by intercellular communication involving eicosanoids.

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