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HIV therapy advances. Early antiretroviral therapy
1National Centre in HIV Epidemiology and Clinical Research, Faculty of Medicine, University of New South Wales, St Vincent's Hospital Medical Centre, Sydney, Australia.
AIDS (London, England)
|September 1, 1994
Abstract
Aim:
To review evidence suggesting that antiretroviral therapy should be initiated at an early stage in HIV infection.
Method:
Review of published data.
Conclusions:
There are arguments both for and against early antiretroviral therapy. Although the reasons against are undoubtedly valid, evidence of greater efficacy, less toxicity and a delay in the development of resistance outweigh the possible disadvantages. Moreover, for some patients, early therapy may provide a chance of future benefits from more useful but currently untried treatments.