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5' noncoding sequence of human IL-10 gene obtained by oligo-cassette PCR walking
C Platzer1, H D Volk, M Platzer
1Institute of Medical Immunology, Humboldt University, Medical School Charité, Berlin, Germany.
DNA Sequence : the Journal of DNA Sequencing and Mapping
|January 1, 1994
Abstract:
A fragment of the human IL-10 gene starting from a Hind III site and including 744 previously unknown bases of the 5' regulatory region was isolated by oligo-cassette PCR walking and the nucleotide sequence was determined. It shows remarkable homology to the mouse IL-10 promoter in regions that have been associated with transcriptional regulation.