Nuclear pores in the apoptotic cell
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E Falcieri1, P Gobbi, A Cataldi
1Istituto di Morfologia Umana Normale, Università di Chieti, Bologna.
The Histochemical Journal
|September 1, 1994
Abstract:
During apoptosis, nuclear pores undergo strong modifications, which are described here in five different apoptotic models. Conventional electron microscopy, supported by freeze-fracture analysis, showed a constant migration of nuclear pores towards the diffuse chromatin areas. In contrast, dense chromatin areas appear pore-free and are frequently surrounded by strongly dilated cisternae. A possible functional significance of this pore behaviour during apoptosis is discussed.