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Treatment of pseudomyxoma peritonei in a geriatric patient population
1Howard University Department of Surgery, Howard University School of Medicine, Washington, DC.
Abstract:
Pseudomyxoma peritonei of appendiceal origin is a disease characterized by the progressive accumulation of mucus ascites within the abdomen and pelvis. Metastatic disease outside the peritoneal cavity is unusual. Gastrointestinal function is lost from external compression of stomach, small bowel, and large bowel. New surgical and regional chemotherapy treatments were used to provide palliation of two patients aged 88 and 85 years. The selection criteria and methodologies for treatment of geriatric patients with pseudomyxoma peritonei are presented.
Insights
Pseudomyxoma peritonei, a rare appendiceal cancer, causes mucus buildup. New surgical and chemotherapy treatments offered palliation for two elderly patients.
Area of Science:
- Oncology
- Gastroenterology
- Geriatric Medicine
Background:
- Pseudomyxoma peritonei (PMP) of appendiceal origin involves progressive mucus ascites accumulation.
- Metastasis outside the peritoneal cavity is uncommon in this condition.
- Gastrointestinal function loss occurs due to external compression.
Observation:
- Two geriatric patients (88 and 85 years old) with PMP were treated.
- The patients experienced loss of gastrointestinal function from mucus accumulation.
Findings:
- Novel surgical and regional chemotherapy approaches were employed for palliation.
- Treatment focused on managing symptoms and improving quality of life in elderly patients.
Implications:
- This case series presents selection criteria and methodologies for treating geriatric PMP patients.
- The findings may inform future treatment strategies for elderly individuals with PMP.
- Highlights the importance of tailored palliative care for elderly cancer patients.