Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Initial experience with a new algorithm for automatic mode switching from DDDR to DDIR mode

I E Ovsyshcher1, A Katz, C Bondy

  • 1Division of Cardiology, Soroka Medical Center, Beer-Sheva, Israel.

Pacing and Clinical Electrophysiology : PACE
|November 1, 1994
PubMed
Summary

New dual-chamber pacemakers with automatic mode switching effectively manage atrial tachyarrhythmias, preventing complications and potentially expanding pacing indications for more patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A novel retro-inverso gonadotropin-releasing hormone (GnRH) immunogen elicits antibodies that neutralize the activity of native GnRH.

Endocrinology·2003
Same author

Noninvasive native fluorescence imaging of head and neck tumors.

Technology in cancer research & treatment·2003
Same author

Variation in the DCP1 gene, encoding the angiotensin converting enzyme ACE, is not associated with increased susceptibility to Alzheimer's disease.

Psychiatric genetics·2003
Same author

Therapeutic potential of curcumin in human prostate cancer-I. curcumin induces apoptosis in both androgen-dependent and androgen-independent prostate cancer cells.

Prostate cancer and prostatic diseases·2002
Same author

Interpretation of spring recession curves.

Ground water·2002
Same author

Ideal vitamin C intake.

BioFactors (Oxford, England)·2002

Area of Science:

  • Cardiology
  • Biomedical Engineering

Background:

  • Dual chamber pacemakers are indicated for patients needing permanent pacing, but atrial tachyarrhythmias can cause complications.
  • VVI/VVIR pacing modes risk loss of atrioventricular (AV) synchrony during sinus activity.
  • Paroxysmal atrial tachyarrhythmias can trigger inappropriate ventricular responses in standard pacemakers.

Purpose of the Study:

  • To evaluate the clinical function of a new DDDR pacemaker with an automatic mode switching (AMS) algorithm.
  • To assess the device's response to paroxysmal atrial fibrillation (PAF) and other atrial tachyarrhythmias.
  • To determine if this technology can safely expand indications for dual chamber pacing.

Main Methods:

  • Implantation of 23 THERA DR (model 7940) DDDR pacemakers with AMS algorithm.

Related Experiment Videos

  • Patient cohort included those with AV block, sick sinus syndrome (SSS), and atrial arrhythmias, including PAF.
  • Follow-up included Holter monitoring and treadmill tests over 1-9 months.

    • Main Results:

    • Eighty-seven episodes of AMS were documented during the follow-up period.
    • The DDDR device successfully switched to DDIR mode during PAF episodes and reverted to DDDR mode upon return to sinus rhythm.
    • Atrial tachyarrhythmias with rates below 182 beats/min did not trigger the AMS feature.

    Conclusions:

    • The DDDR pacemaker with AMS demonstrated appropriate function in managing PAF.
    • This technology shows promise for extending the use of dual chamber pacing in patients with atrial tachyarrhythmias.
    • Early clinical experience suggests safety and efficacy for this novel pacing approach.