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Related Experiment Videos

Clinical evaluation of a dual sensor, rate responsive pacemaker

S Sinha1, R J Schilling, G C Kaye

  • 1Department of Cardiology, Hull Royal Infirmary, United Kingdom.

Pacing and Clinical Electrophysiology : PACE
|November 1, 1994
PubMed
Summary

Dual sensor pacemakers, like the Topaz model 515, showed appropriate rate responses during exercise. However, adjusting sensor contributions did not significantly alter the onset of rate response in patients.

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Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Exercise Physiology

Background:

  • Dual sensor pacemakers aim for improved physiological rate response compared to single sensor devices.
  • The Topaz model 515 utilizes both QT interval and activity count (ACT) for rate modulation.
  • Fine-tuning sensor contribution is hypothesized to optimize pacemaker response during varied activities.

Purpose of the Study:

  • To evaluate the rate response of the Topaz 515 dual sensor pacemaker during different exercise modes.
  • To investigate the impact of adjusting relative sensor contributions (QT vs. ACT) on pacemaker rate response.
  • To assess pacemaker response to isometric exercise and simulated false-positive activity signals.

Main Methods:

  • Eleven patients with Topaz 515 pacemakers underwent three standard exercise tests with varying sensor settings.

Related Experiment Videos

  • Sensor settings included different blends of QT and ACT contributions and activity threshold adjustments.
  • Responses to isometric exercise and a simulated false-positive activity (tapping) were also recorded.

    • Main Results:

    • No significant differences in the onset of rate response were observed across the three sensor settings.
    • Pacemaker rate increased appropriately during treadmill exercise and isometric exertion.
    • Simulated false-positive activity (tapping) resulted in a transient, but controlled, increase in paced rate, indicating effective sensor cross-checking.

    Conclusions:

    • The Topaz 515 pacemaker demonstrates satisfactory rate response during both dynamic (treadmill) and isometric exercise.
    • Minor adjustments to the relative contributions of QT and activity sensors do not predictably modify the initiation of pacemaker rate adjustments.
    • Dual sensor pacemakers offer robust physiological adaptation, but precise control over response onset via sensor blending requires further investigation.