Prevention of lung cancer through the use of knowledge on asbestos and other work-related causes--Norwegian...

This review attempts to estimate the contribution of different known work-related causes of lung cancer in the Norwegian male population in order to predict the potential of prevention of work-related cases. The presented estimates are based on data from epidemiologic studies made in Norway, but may be of significance for other countries with a similar work-force structure. Over the past decade asbestos-related lung cancer appears to have contributed about two-thirds of the lung cancers that have been related to work exposure in Norway, for example, possibly 125-175 of the 1100 cases that occurred among Norwegian men in 1987. The potential for prevention is, however, greater due to synergism. To a less extent compounds of nickel and chromium have also contributed, along with exposure to polycyclic aromatic hydrocarbons, radon daughters, seafaring work, and other, less significant specific and nonspecific determinants of lung cancer.