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MR of isolated leptomeningeal glioma

O Krief1, L Monnier, P Cornu

  • 1Department of Neuroradiology, Hospital of Pitié-Salpêtrière, Paris, France.

Insights

High-grade gliomas can mimic leptomeningeal carcinomatosis on MRI. Superficial gliomas should be considered in the differential diagnosis for isolated meningeal enhancement.

Area of Science:

  • Neuroimaging
  • Neuroradiology
  • Oncology

Background:

  • Leptomeningeal carcinomatosis presents as diffuse leptomeningeal enhancement on MRI.
  • Differential diagnosis is crucial for appropriate patient management.

Observation:

  • A case of high-grade glioma demonstrated imaging findings that mimicked leptomeningeal carcinomatosis.
  • The glioma exhibited superficial enhancement patterns within the meninges.

Findings:

  • Magnetic resonance (MR) imaging revealed a high-grade glioma with atypical meningeal enhancement.
  • The imaging characteristics were indistinguishable from leptomeningeal carcinomatosis in this instance.

Implications:

  • Superficial gliomas represent an important consideration in the differential diagnosis of isolated meningeal enhancement.
  • Neuroimaging interpretation requires awareness of uncommon glioma presentations to avoid misdiagnosis.

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