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Related Experiment Videos

Tricuspid valve dysfunction in the transplanted heart

R D Stahl1, S V Karwande, S L Olsen

  • 1Utah Cardiac Transplant Program, Salt Lake City.

The Annals of Thoracic Surgery
|February 1, 1995
PubMed
Summary

Severe tricuspid regurgitation after heart transplant is rare but can occur. Ruptured chordae tendineae, potentially from endomyocardial biopsies, may cause this complication.

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Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Transplantation Medicine

Background:

  • Mild tricuspid regurgitation is common post-orthotopic heart transplant due to anastomosis geometry.
  • Severe tricuspid regurgitation requiring intervention is infrequent in heart transplant recipients.

Observation:

  • A study at the University of Utah identified 5 cases (0.95%) of severe tricuspid regurgitation among 526 heart transplant patients between 1985 and 1993.
  • Echocardiography and intraoperative findings revealed ruptured chordae tendineae of the tricuspid valve.

Findings:

  • Severe tricuspid regurgitation in these patients was attributed to ruptured chordae tendineae.
  • Surgical repair or replacement of the tricuspid valve yielded positive outcomes.

Implications:

Related Experiment Videos

  • Endomyocardial biopsy procedures may inadvertently cause injury leading to tricuspid valve chordal disruption.
  • Further research is warranted to explore preventative measures during endomyocardial biopsies to mitigate tricuspid valve complications.