[Treatment of pylethrombosis with alteplase. Description of a clinical case]

The authors report a case of venous pylethrombosis of the proximal splanchnic circuit treated with rt-PA (alteplase) for the first two days and later associated with high doses of heparin. rt-PA demonstrated a good level of efficacy with the partial resolution of the thrombus already after the first administration and in spite of the late commencement of therapy.