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Updated: Aug 24, 2026

07:36
Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
The effect of early hypoxy upon the development of rats and mice. II. Foetal effects
Abstract:
The late, foetal effect of temporary hypoxy--performed by uterine vascular clamping--during the preimplantation period (day 2, 3 and 4 of pregnancy) was controlled in rats. The main detected effects were: lowering of the number of implantation sites and of the mean number of living foetuses; lowering of the mean foetal weight: increased percentage of resorptions and partial retardation of skeletal development. No structural anomalies were registered.

