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Management of bacterial urinary tract infections in adults
J Hatton1, M Hughes, C H Raymond
1University of Kentucky Medical Center, Lexington.
Objective:
To provide a comprehensive review of the diagnosis and therapeutic management considerations in patients with urinary tract infections (UTIs).
Data Sources:
A MEDLINE search was used to identify pertinent English language literature, including reviews. Infectious disease textbooks were used for background information.
Study Selection:
Clinical trials evaluating drug therapy in a variety of patient populations with UTIs were reviewed.
Data Extraction:
Background information was obtained from comprehensive reviews. Drug dosing strategies and efficacy comparisons were extracted from the investigations in this area.
Data Synthesis:
Information was processed to provide general guidelines and resources for practitioners to use in managing UTIs.
Conclusions:
There are a number of useful antibiotics for the management of UTIs. The distinctions between infection severity and underlying risk factors within a given population influence the appropriateness of drug selection and duration of treatment.